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This signaling axis is central to BPC-157s ability to restore endothelial function following insult/damage to the human body

In fact, it comes from a protein found in gastric juice

Hormonal Regulation Preliminary Research Research demonstrates DSIP's broad effects on neuroendocrine function including modulation of growth hormone release patterns, luteinizing hormone secretion, and thyroid hormone metabolism that may contribute to its sleep-promoting and regenerative properties

MOTS-c converges on AMPK, the cells energy sensor, and under metabolic stress relocates to the nucleus to help regulate gene expression [4]